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Mathilde Boissel
Curriculum Vitæ
With a master’s degree in Applied Mathematics and Statistics, I like projects with mental challenges, precision and team work. I have skills in programming and statistical methods, with a solid educational foundation and a passion for science.
Professional & Research Experience
Biostatistician Engineer
UMR8199 - University of Lille
Lille, France
10/2018 - Today
Activities: Genomic studies in the diabetes and obesity field
- GWAS, EWAS, eQTL, mQTL, DE analyses, Rare variant analyses (burden and dispersion test)
- Statistical modelling, Clustering methods, Methodological support
- DNA microarray, Methylation chip and Next-Generation Sequencing
- Use of various DB : 1000 genomes, Ensembl, dbNSFP, COSMIC, DAVID
- Involved in several CONSORTIUM (CHARGE, CKDGen, IMIDIA)
Biostatistician Engineer
UMR8199 - CNRS
Lille, France
10/2015 - 10/2018
Activities: Genomic studies in the diabetes and obesity field
Intern Modelling a treatment decision-making support
Centre de Traitement des Données - CNO
Caen, France
04/2015 - 09/2015
Activities: Modelling a recommendation system, applied for Hodgkin’s lymphoma patients
- Model combinating survival probabilities and patient ratings on their quality of life and iatrogenic effects, tested by simulation
- Interactive decision-making support (developped with Drupal, WAMP, HTML, PHP and JS)
- Introduction to data managment (Clinsight eCRF and CDISC)
Fixed term contract Project VegeDurable 2
Université de Caen
Caen, France
01/2014 - 04/2014
Activities: Research of the effects of fertilizers, density of soil and water concentration in carrot production
- Statistical modelling and clustering of measures taken in the carrot plot
Intern Estimating of the convolution kernel of the hemodynamic response for the treatment of fMRI data
Cyceron - Site GANIL
Caen, France
05/2014 - 06/2014
Activities: Estimation of parameters of hemodynamic response function
- Introduction to treatment of fMRI data (with R and Matlab), BOLD signal, software SPM, ImageJ
Intern –volontary- Methodologist
Lab COMETE - INSERM - CHU
Caen, France
06/2013 - 06/2013
Activities: Analysis with R and SAS of data about hypovigilance on roads
Education
Master Degree of Science (M. Sc), in Applied Mathematics “MASS”
University of Caen
Caen, France
2013 - 2015
Speciality: Decision support in business
- Statistics (R, SAS, VBA Excel)
- Computer science (POO Python, MySQL, HTML5, CSS3)
- Mathematics of the decision
- Economic and social sciences (Macro and Micro, Management control, Marketing, Optimization, Supply chain, Project management)
Bachelor Degree of Science (B. Sc), in Applied Mathematics “MASS”
University of Caen
Caen, France
2010 - 2013
Broad-spectrum of knowledge theoretical and practical subjects as statistics, computing, economy, survey and polls, marketing, econometrics, bio-statistics, management control, logistic management…
Scientific Baccalauréat, Speciality: Mathematics
Lycée Le Verrier
Saint-Lô, France
2007 - 2010
R Packages
CARoT: Centralised and Automated RepOrting Tools
mcanouil, mboissel and Ning-L
GitHub
juil.. 2019
https://github.com/mboissel/CARoT/
Oral/Poster communications
Feedback on RNA-seq data analyses
Journal Club - UMR8199
Lille, France
28/05/2018
Analyse de variants rares issus de données de séquençage à haut débit
Working group RIS Statistics and Genomics
Paris, France
12/10/2018
Publications (9)
Loss-of-function mutations in MRAP2 are pathogenic in hyperphagic obesity with hyperglycemia and hypertension.
Morgane, Baron, Philippe, Froguel and Amelie Bonnefond
N/A
Nov. 2019
A catalog of genetic loci associated with kidney function from analyses of a million individuals.
Matthias Wuttke and Cristian Pattaro
N/A
May 2019
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure
Yun Ju Sung and Alanna C Morrison
N/A
Apr. 2019
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
Amy R Bentley and Adrienne Cupples
N/A
Mar. 2019
Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
Paul S de Vries and Alanna C Morrison
N/A
Jan. 2019
Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.
Tuomas O Kilpelainen and Ruth J. F. Loos
N/A
Jan. 2019
Type 2 diabetes-associated variants of the MT2 melatonin receptor affect distinct modes of signaling.
A Karamitri and Ralf Jockers
N/A
Aug. 2018
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
Mary F. Feitosa and Daniel Levy
N/A
Jun. 2018
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.
Yun J. Sung and Daniel L. Chasman
N/A
Mar. 2018
INTEREST
- Sports: Martial art (2y Karaté, 2y Jujitsu, 6y Judo), sports needing rigor, respect and humility
- Trips: European big Cities, Moto bike, Hike
- Sharing : Steering committee in a UseR group under construction at Lille, steering committee in the CNRS working group RIS Statistics and Genomics
- Languages: English (professional, Certification C.L.E.S), French (Mother tongue)